The risk for heart attack, stroke, and co. to determine earlier and more precise
Cardiovascular disease is the leading cause of death in Germany. Researchers have now been able to identify a new Marker. The findings of this research could contribute to the risk for such diseases can be determined in the future earlier and more accurately.
More and more deaths diseases of the heart
According to a report from the German heart Foundation, the number of deaths increased as a result of heart disease. Also in other countries of the Western world, cardiovascular diseases are the most common causes of death. By a healthier life-style, approximately every second case of death could be avoided, as experts reported recently. German researchers have now gained new insights into cardiovascular disease.
Researchers were able to identify new markers
Especially older people are affected by cardiovascular disease. In addition to the life expectancy cardiovascular diseases can also limit the quality of life enormously.
Researchers at the German Institute for nutritional research Potsdam-Rehbrücke (DIfE) have now been able to identify a new Marker.
Accordingly, the Protein Chemerin, gives insights into the unknown mechanisms of the disease development and could in future be used to determine the risk for heart attack, stroke, and co.even earlier, and more precise.
The results of the study were published in the current issue of the “Journal of the American College of Cardiology”.
Offered material is mainly formed in fat tissue
As the DIfE in a communication, Chemerin, is a messenger substance (Adipokine), the tissue mainly in the fat and in the liver, kidneys and pancreas is formed.
He contributes to the first, identical, undifferentiated cells of the adipose tissue specialized for certain tasks in terms of function and shape.
In addition, Chemerin attracts immune cells to injured tissue, trigger immediate inflammation and in this way infections to fend off. The signal protein is thus part of the finely regulated alarm system of the body.
“The System at the seams, threatening to atherosclerosis, heart attack and stroke,” explains Dr. Krasimira Aleksandrova, of the studied at the DIfE, such as the Interplay between nutrition, body composition, and immune system affects of age-related diseases.
Risk for cardiovascular disease you to more accurately predict
The exact relationships between inflammatory reactions and cardiovascular diseases are not yet fully elucidated.
In order to bring more light into the Dark, and analyzed by the Team of Aleksandrova, the blood samples of a total of 2,500 men and women. Based on the studies formed the data of the Potsdam EPIC study, with over 27,500 study participants.
The scientists observed for the first time, that the concentration of Chemerin in the blood is already increased before the Onset of heart attacks and strokes.
Thus, Chemerin might be used in the future as an indicator of the risk for cardiovascular disease more accurately predict.
“Our results confirm that the signal protein Chemerin for inflammation processes as well as for the development of cardiovascular diseases plays a very important role,” says Aleksandrova.
“This track should necessarily be followed. The Understanding of the exact functions of Chemerin in the future could improve the search for new prevention therapies and drugs.“ (ad)