A British vaccine against the Coronavirus seems to be according to a study, sure, and boost the immune system. The resources of the University of Oxford and the British pharmaceutical company AstraZeneca works in two ways:
It promotes both the formation of specific antibodies as well as T-cells, both for immune defense is important. The results of the experts in the British medical journal “The Lancet” (20 reported. July).
First results from the Phase 1/2 study were already announced last week. The Experiments with 1077 healthy individuals were classified as promising.
The significant immune response was still 56 days after vaccination and could possibly be due to a second dose of extended States in “The Lancet”.
The vaccine offers enough protection?
Nevertheless, it is still unclear whether the vaccine, called ChAdOx1 nCoV-19 offer sufficient protection, according to the experts. In order to clarify this question, have already started in Brazil, more Tests with Thousands of volunteers in a Phase III study. The vaccine is based on certain manipulated viruses that normally occur in monkeys.
“There must be a lot of work done before we can confirm that our vaccine will help to cope with the Covid-19 pandemic,” said co-author Sarah Gilbert of the University of Oxford.
The vaccine triggered according to the researchers, side effects such as fatigue and headaches, but nothing Serious. The UK already ordered doses 100 million doses of the Vaccine.
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Researchers in China are testing also vaccine
Also on 20. July presented by Chinese researchers in “The Lancet” the success of a vaccine in a Phase 2 trial with more than 500 people.
Also, this was safe and provoked a reaction of the immune system such as antibodies or corresponding immune cells (T-cells) in the blood, writes the Team led by Feng-Cai Zhu of the Jiangsu Provincial Center for Disease Control and Prevention in Wuhan.
Any side effects were fever thus, for example, fatigue, or pain at the injection site and were mild in most cases. Also, this vaccine still needs to be checked whether the triggered immune system works sufficiently.
Internationally, there is a race of scientists and pharmaceutical companies to a Corona vaccine. The funds from Oxford is one of the promising candidates rich. Currently be tested, according to the world health organization (WHO) more than 20 vaccines in clinical trials in humans.
Sources
- Zhu, F. et al. (2020): Immunogenicity and safety of a recombinant adenovirus type 5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial, retrieved on 21.07.2020: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31605-6/fulltext
- Folegatti, P. et al. (2020): Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial, retrieved on 21.07.2020: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext
Deutsche Presse-Agentur (dpa)
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