The longer the pandemic lasts, the novel Coronavirus Sars-CoV-2, the more information Researchers are able to carry from all over the world via the associated disease.
Thus, risk factors that make a critical course of disease more likely, and is confirmed to be discovered can.
Obesity increases susceptibility for Covid-19
High body fat increases the proportion of the organism and the immune system is negatively affected and the risk for various diseases, including pneumonia, is no more news.
Current studies now show, however, that obesity can be Affected truly fatal, because they are more susceptible to the Sars-CoV-2-pathogens as a normal weight.
Scientists from France and China have taken place in different studies, these effects of Obesity on Covid-19-patients in more detail.
The severity of the disease increases with BMI
The research team led by Arthur Simonnet from the University hospital of Lille, referred to the data of all the Covid-19-Patients with a, the of 27. February, am to 5. April in the ICU, 124 were treated in total.
The scientists found that slightly more than three-quarters of the Overweight patients hospitalized, or even severe obesity had.
Of the 124 patients, 85 had to be a tube ventilated. Of these persons, 56% had a Body Mass Index of over 30 and a further 38 percent have a BMI of over 35.
The patient data clearly show that with increasing body weight in the course of the disease was drastic, and the need for artificial ventilation was more likely.
“The severity of the disease increased with the BMI,” conclude the researchers in the report, which was in the journal ‘Obesity’ published. “Obesity is a risk factor for the severity of Sars-CoV-2.”
In the gallery: 10 tips to protect yourself against viruses and bacteria
BMI of the Surviving low
A further study under the direction of YD Peng from China confirms these results.
The researchers analyzed 112 patients between the age of 20. January and the 15. February had been delivered in the Union Hospital in Wuhan in.
The Figures clearly show that 88.2 percent of the Covid-19 deceased persons had a BMI of over 25 and were thus overweight or obese.
In contrast, only 18.9 percent had the Survivors with a BMI higher than 25.
Adipose tissue provides an attack surface for viruses
First approaches to an explanation of why overweight people are more susceptible to the Coronavirus, which delivers a Preprint study by researchers at the General hospital in Beijing.
According to this so-called ACE2 are receptors on the cells in the fat tissue. Exactly, these receptors are needed for the corona virus, the cells to dock and to multiply then.
People with more fat tissue may thus provide more attack surface for viruses and therefore be more susceptible.
“We found that the ACE2 Expression in adipose tissue was higher than in the lung tissue, indicating that fat tissue may also for Sars-CoV-2 is vulnerable,” – said in the research report.
Body fat around the abdominal breathing can affect
Add to that a high body fat percentage proven to be a result, neurotransmitters are released that cause inflammation promote and, accordingly, the body’s own immune reaction to negative affect.
In addition, overweight people in many cases suffer from shortness of breath; the body fat around the abdominal area, breathing and lung function can negatively affect and restrict.
These initial findings clearly indicate that Obesity represents in addition to the age is another important risk factor in the course of Covid-19.
People with Overweight or obesity should not, therefore, particularly in this time a lot of caution to the day, to infect.
Sources
- Simonnet, A., et al. (2020): High prevalence of obesity in severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV 2) requiring invasive mechanical ventilation, archived from the original on 12.05.2020 https://onlinelibrary.wiley.com/doi/abs/10.1002/oby.22831
- YD, P., et al. (2020): Clinical characteristics and outcomes of 112 cardiovascular disease patients infected by 2019-nCoV, retrieved on 12.05.2020 https://www.ncbi.nlm.nih.gov/pubmed/32120458
- Jia, X., et al. (2020): Two Things about COVID-19 Might Need Attention, retrieved on 12.05.2020 https://www.preprints.org/manuscript/202002.0315/v1
Cornelia Bertram
*The article “Coronavirus: Overweight Covid may be published-19-course of” worse is of FitForFun. Contact with the executives here.